INTRODUCTION
• Biomarkers indicate the presence of current or future disease. With genetic testing, these are generally alterations within DNA, RNA, or proteins.
• These biomarkers can be tested by targeted gene or analyte panels, or by broader genomic and transcriptomic sequencing and other multiomic approaches.
• Testing genetic biomarkers allows for disease diagnosis, treatment determination, or surveillance of emergent symptoms. This information often provides recurrence risk and other useful information for patients’ families as well.
• Within the United States, a review of each state’s status for passing biomarker testing legislation is described.
