Test Updates // Oncology // FISH Panel Probes (Dec 2019)

Dear Valued Clients,

Effective December 16, 2019, in a continuing effort to optimize our offerings, Baylor Genetics has updated four FISH panels and will begin offering three new FISH panels. The changes to the probes used in each FISH panel are based on the latest recommendations from the World Health Organization.

 

The FISH probes for the following Oncology FISH test codes have been updated:

 

Test Code Test Description Current FISH Panel New FISH Panel
8010 Acute Lymphoblastic Leukemia Panel MYB
CDKN2A
BCR/ABL
KMT2A
ETV6/RUNX1
IGH
CDKN2A
BCR/ABL
KMT2A
IGH
CEP 4
CEP 10
8015 Multiple Myeloma Panel CEP 9
RB1
P53
IGH
SNRPN
CKS1B/CDKN2C
D7S486
CEP 9
RB1
P53
IGH
SNRPN
8020 Non-Hodgkin Lymphoma Panel BCL6
ALK
ATM
IGH
P53
BCL6
IGH/CCND1
MYC
MALT1
BCL2
8040 Chronic Lymphocytic Leukemia Panel CEP 12
ATM/p53
MYB
D13S319
IGH
CEP 12
ATM/p53
MYB
D13S319
IGH
IGH/CCND1

 

 

In order to update our Oncology FISH catalog, we will be offering the following new tests:

 

Test Code Test Description New FISH Panel
8790 Multiple Myeloma IgH Rearrangement Panel IGH/FGFR3
IGH/MAF
IGH/CCND1
8791 Eosinophilia Panel PDGFRB
FGFR1
JAK2
PDGFRA/CJIC2/FIP1L1
CBFB
8792 ALL Pediatric Panel BCR/ABL
KMT2A
ETV6/RUNX1
CEP 4
CEP 10
TCF3/PBX1

 

In addition, for myeloma samples we will begin offering Plasma Cell Enrichment in order to enhance our detection of cytogenetic abnormalities by FISH in patients with Plasma cell Neoplasms.

If you have specific questions regarding these updates, please contact your Baylor Genetics account representative or feel free to call our Client Relations Division at 1.800.411.4363.

Thank you for your continued business.

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