Test Updates // Oncology // FISH Panel Probes (October 2019)

Dear Valued Clients,

Thank you for your continued trust in Baylor Genetics as your genetic testing partner.

As we continually upgrade and refine our test menu and services, we want you to be the first to know of changes that may affect your testing with us.

Effective October 1^st, 2019, the following test updates will occur:

The probes on the following FISH panels will be updated:

• ALL FISH Panel (test code 8010): CDKN2A del, BCR/ABL gene fusion, KMT2A rearrangement, IGH rearrangement, CEP 4 gain, CEP 10 gain
• CLL FISH Panel (test code 8040): Trisomy 12, ATM del, p53 del, MYB del, 13q del, IGH rearrangement, IGH/CCND1 fusion
• MM Fish Panel (test code 8015): Trisomy 9, RB1 del, IGH rearrangement, Trisomy 15, p53 del
• NHL FISH Panel (test code 8020): BCL6 rearrangement, IGH/CCND1 fusion, MYC rearrangement, MALT1 rearrangement, BCL2 rearrangement

In addition, for myeloma samples we will begin offering Plasma Cell Enrichment in order to enhance our detection of cytogenetic abnormalities by FISH in patients with Plasma Cell Neoplasms.

Transition period

If you are using an older test requisition form after October 1^st, 2019, orders for ALL FISH Panel (test code 8010), CLL FISH Panel (test code 8040), MM FISH Panel (test code 8015), or NHL FISH Panel (test code 8020) will automatically include the updated probes.

The updated Tumor Analysis requisition will be available to download on October 1^st, 2019.

If you have specific questions regarding these updates, please contact your Baylor Genetics account representative or feel free to call our Client Relations Division at 1.800.411.4363.

Thank you for your continued business.