Effective March 10, 2014, the Medical Genetics Laboratories at Baylor College of Medicine will supplant Test Code 3300 – Autosomal Dominant Progressive External Ophthalmoplegia (ad-PEO) Panel with Test Code 2140 – PEO Panel by Massively Parallel Sequencing (BCM-MitomeNGSSM).
Test Code 2140 – PEO Panel by Massively Parallel Sequencing (BCM-MitomeNGSSM) is superior to the discontinued test in many respects. The new features are:
- Eight nuclear encoded genes involved in Progressive External Ophthalmoplegia (PEO) are analyzed simultaneously by Massively Parallel Sequencing (MPS) technology.
- All coding exons and adjacent intronic regions of these genes are 100% covered. The average read depth of the targeted regions is 700X.